BIGG

American Society of Hematology 2020 guidelines for sickle cell disease: transfusion support

Chou, Stella T; Alsawas, Mouaz; Fasano, Ross M; Field, Joshua J; Hendrickson, Jeanne E; Howard, Jo; Kameka, Michelle; Kwiatkowski, Janet L; Pirenne, France; Shi, Patricia A; Stowell, Sean R; Thein, Swee Lay; Westhoff, Connie M; Wong, Trisha E; Akl, Elie A.

Blood adv. (Online); 4 (2), 2020

Red cell transfusions remain a mainstay of therapy for patients with sickle cell disease (SCD), but pose significant clinical challenges. Guidance for specific indications and administration of transfusion, as well as screening, prevention, and management of alloimmunization, delayed hemolytic transfusio...

Anemia, Sickle Cell/prevention & control, Anemia, Sickle Cell/blood, Anemia, Sickle Cell/complications, Blood Transfusion/methods, Hemolytic Plaque Technique/methods

Fulltext

Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) of Pneumococcal Vaccines for Immunocompromised Children Aged 6 through 18 Years

GRADE was used to evaluate 13-valent Pneumococcal Conjugate Vaccine (PCV13) for routine use among immunocompromised children aged 6 through 18 years. Evidence of benefits, harms, values and preferences, and cost-effectiveness were reviewed in accordance with GRADE methods.[1] The primary policy question...